Sinonasal non-keratinizing squamous cell carcinoma with nasal skin extension as the initial presentation
| Autor: | A. Neil Crowson, Sara Metcalf, Ruifeng Guo |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pathology
medicine.medical_specialty Histology integumentary system medicine.diagnostic_test business.industry Context (language use) Dermatology medicine.disease Malignancy Pathology and Forensic Medicine stomatognathic diseases Transitional cell carcinoma Keratinizing Squamous Cell Carcinoma Dysplasia Biopsy medicine Histopathology Presentation (obstetrics) business |
| Zdroj: | Journal of Cutaneous Pathology. 39:791-794 |
| ISSN: | 0303-6987 |
| DOI: | 10.1111/j.1600-0560.2012.01939.x |
| Popis: | Sinonasal non-keratinizing squamous cell carcinoma (SCC), previously designated as transitional cell carcinoma or cylindrical cell carcinoma, is an uncommon malignant neoplasm with distinct histopathological features, considered to be a low-grade malignancy that usually occurs in elderly patients. Extensive local invasion is uncommon. Here we report a case of 90-year-old woman whose original presentation was as erythematous nasal skin nodules, biopsy of which showed a dermal tumor with features of sinonasal non-keratinizing SCC. No epidermal dysplasia was present. A subsequent computed tomography scan confirmed the presence of an endophytic tumor on the nasal sidewall. The initial presentation of sinonasal non-keratinizing SCC as a skin lesion is previously unreported to our knowledge. Diagnosis in this context requires accurate evaluation of the histopathology as well as a comprehensive knowledge of pathology specific to this anatomic location. |
| Databáze: | OpenAIRE |
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