Dissolution of cholelithiasis in a Cavalier King Charles Spaniel receiving conservative management with ursodeoxycholic acid
| Autor: | Katie E McCallum, Marie-Aude Genain, Frederik Allan, Penny Watson, Benjamin John Harris |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Conservative management 040301 veterinary sciences biology.animal_breed Anorexia Gastroenterology 0403 veterinary science Internal medicine medicine Cavalier King Charles spaniel General Veterinary medicine.diagnostic_test biology business.industry Blood biochemistry Intermittent vomiting 0402 animal and dairy science 04 agricultural and veterinary sciences medicine.disease 040201 dairy & animal science Ursodeoxycholic acid Abdominal ultrasonography Pancreatitis medicine.symptom business medicine.drug |
| Zdroj: | Veterinary Record Case Reports. 8 |
| ISSN: | 2052-6121 |
| DOI: | 10.1136/vetreccr-2020-001206 |
| Popis: | A six-year-old female neutered Cavalier King Charles Spaniel presented with recurrent diarrhoea, intermittent vomiting and anorexia. She was diagnosed with partially obstructive cholelithiasis with concurrent suspected chronic pancreatitis based on abdominal ultrasonography and blood biochemistry. The dog responded to conservative management with ursodeoxycholic acid (UDCA), paracetamol and a low-fat diet with resolution of clinical signs attributable to obstructive cholelithiasis and near-complete dissolution of the cholelith at follow-up eight months after presentation. In human medicine, UDCA has been reported to be effective in cholelith dissolution, prevention of cholelith formation and resolution of clinical signs due to cholelithiasis but the non-surgical literature in veterinary medicine is limited. To the authors’ knowledge, this is the first reported case of dissolution of a cholelith in a dog receiving conservative management. |
| Databáze: | OpenAIRE |
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