Cardiovascular effects of fission neutron or 60Co γ exposure in the B6CF1 mouse
| Autor: | Bruce A. Carnes, David G. Hoel |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Physics
Cobalt Radioisotopes Radiological and Ultrasound Technology business.industry Radiochemistry Gamma ray Cvd mortality 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Relative biological effectiveness Radiology Nuclear Medicine and imaging Neutron Fission neutron National laboratory Dose rate Nuclear medicine business |
| Zdroj: | International Journal of Radiation Biology. 93:563-568 |
| ISSN: | 1362-3095 0955-3002 |
| Popis: | In this study, the B6CF1 mice from the JANUS program at the Argonne National Laboratory were analyzed for increased cardiovascular disease (CVD) mortality from 60Co γ ray or fission neutron exposures administered in either a single dose or protracted weekly doses. The data used for this study represent the last studies conducted at Argonne and have been archived for at least 15 years. CVD mortality increased in a dose-dependent manner from γ rays as well as from neutron exposures. The relative biological effectiveness (RBE) for neutrons is about 4 or 5. CVD mortality appeared to be enhanced when the dose was protracted, with a DDREF (dose and dose rate effectiveness factor) in the range of 0.4-0.45 for neutron and gamma ray exposure, respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |