The role of the lungs and liver in the kinetics of transplanted lymphoid leukemia L1210 cells labelled with radiochromium 51Cr

Autor:	Jan Doroszewski, Janusz Skierski
Rok vydání:	1977
Předmět:	Cancer Research Lymphatic leukemia Pathology medicine.medical_specialty Lung Kinetics Hematology Biology medicine.disease Leukemia L1210 Spleen puncture medicine.anatomical_structure Oncology medicine L1210 cells Neoplasm Lymphoid leukemia
Zdroj:	Leukemia Research. 1:309-313
ISSN:	0145-2126
DOI:	10.1016/0145-2126(77)90050-9
Popis:	The role of the lungs and the liver in the kinetics of lymphatic leukemia L1210 cells was studied in mice. Radiochromium ( 51 Cr) labelled cells were introduced intravenously and intraportally via a spleen puncture. Quantitative data were obtained on the distribution of transplanted labelled cells in tissues and organs, for two different time intervals. Some differences in the interaction between the cells and the lung and between the cells and the liver have been revealed. The cells taken up in the liver, or those passing through it, undergo functional changes and a great number of them are probably destroyed there. The cells taken up in the lungs are partially released undamaged and/or in the form of insoluble fragments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::14f36a9132f07aba539536432d452759 https://doi.org/10.1016/0145-2126(77)90050-9 Zobrazit plný text záznamu