Dexamethasone and flavor neophobia in hamsters

Autor: Roderick Wong, Marne Owen, Christopher B McBride
Rok vydání: 1994
Předmět:
Zdroj: Psychobiology. 22:203-208
ISSN: 0889-6313
Popis: The effects of dexamethasone (DEX) on the reactions of male and female hamsters to novel flavors were studied in an attempt to assess the role of novelty-induced stress in flavor neophobia. DEX is a synthetic glucocorticoid of wide-ranging effects including the blocking of adrenal response to stress in pregnant hamsters. If reactions to novel flavors are mediated by stress, DEX-treated hamsters should show an attenuation of flavor neophobia in relation to nontreated animals. Neophobic reactions were assessed by comparing the hamsters’ latency to pouch a novel-flavored nut in comparison with a familiar unflavored one. Flavor neophobia was manifested in response to novel salty, sweet, or sour nuts when male and female hamsters were tested under the control (no-DEX) condition. Similar results were obtained with DEX-treated animals, with one exception. There was an interaction indicating that DEX-treated females showed enhanced neophobic reactions to a sucrose-flavored nut. The theoretical implications of these findings are discussed.
Databáze: OpenAIRE