GONADOTROPIC HORMONE ASSAYS OF HUMAN MALE URINE1

Autor: Carl G. Heller, Emily J. Heller, Elmer L. Sevringhaus
Rok vydání: 1941
Předmět:
Zdroj: Endocrinology. 29:1-7
ISSN: 1945-7170
0013-7227
DOI: 10.1210/endo-29-1-1
Popis: ATTEMPTS are being made through the assay of gonadotropic hormone in human urine to furnish an aid in the clinical diagnosis and treatment of gonadal dysfunctions, as well as to add further information on the role of this hormone in the relationship between the pituitary and the gonads. Although even the best assay methods are only roughly quantitative, and many of the findings probably misleading and unreliable, sufficient progress has been made in recent years to justify the hope that such studies may eventually leave the research laboratory, and enter the field of practical application. We have been able to apply greatly improved extraction and assay technics for gonadotropic hormone to routine analyses of urine. A study of the excretion rate of this hormone in a series of women of various ages revealed that urinary gonadotropic concentration was low in menstruating women, increased markedly at the menopause, and remained consistently high during the post-menopausal period and senility (1).
Databáze: OpenAIRE