Evaluating improvements in cardiac dosimetry in breast radiotherapy and comparison of cardiac sparing techniques
| Autor: | Martin C. Tom, Elizabeth Obi, Ahmad Masroor Karimi, Sheen Cherian, Eva Suarez, Chirag Shah, Bindu V. Manyam, C.W. Fleming, Mihir Naik, Rahul D. Tendulkar |
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| Rok vydání: | 2019 |
| Předmět: |
business.industry
medicine.medical_treatment Breast radiotherapy Retrospective cohort study Breast radiation medicine.disease 030218 nuclear medicine & medical imaging Radiation therapy 03 medical and health sciences Prone position Left breast 0302 clinical medicine Breast cancer 030220 oncology & carcinogenesis Medicine Dosimetry business Nuclear medicine |
| Zdroj: | Journal of Radiation Oncology. 8:305-310 |
| ISSN: | 1948-7908 1948-7894 |
| DOI: | 10.1007/s13566-019-00400-3 |
| Popis: | Data from Darby et al. demonstrated that cardiac dose in patients undergoing breast radiation therapy is associated with cardiac events. Cardiac dose is primarily dependent on treatment laterality and treatment fields. More recently, techniques such deep inspiratory breath hold (DIBH) and prone positioning have been used as cardiac sparing techniques. The purpose of this study is to assess changes in cardiac dosimetry with cardiac sparing techniques. This retrospective study included breast cancer patients treated from 2010 to 2018 at a single institution. Mean heart dose (MHD) was analyzed with respect to treatment era, laterality, cardiac sparing technique, and treatment fields, including regional nodal irradiation (RNI) and internal mammary nodal irradiation (IMNI). Seven hundred sixty-five patients were included in this study. Average MHD was 1.87 Gy for left-sided cases and 0.71 Gy for right-sided cases (p |
| Databáze: | OpenAIRE |
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