Asymmetric Reactions Catalyzed by Chiral Metal Complexes. LIV. Effects of the diarylphosphino groups of modified DIOPs on the enantioselectivity and the catalytic activity of their rhodium(I) complexes in the catalytic asymmetric hydrogenations of enamides

Autor:	Mitsuo Chiba, Kazuo Achiwa, Toshiaki Morimoto
Rok vydání:	1992
Předmět:	Olefin fiber Asymmetric hydrogenation Enantioselective synthesis Cationic polymerization chemistry.chemical_element General Chemistry General Medicine Medicinal chemistry Rhodium Catalysis chemistry Drug Discovery Organic chemistry Efficient catalyst
Zdroj:	Chemical and Pharmaceutical Bulletin. 40:2894-2896
ISSN:	1347-5223 0009-2363
Popis:	Remarkable effects of the substituted diphenylphosphino groups of modified DIOPs on the enantioselectivity and the catalytic activity were observed in the asymmetric hydrogenation of an electron-rich olefin such as enamide using their rhodium(I) complexes as the catalyst. The cationic rhodium(I) complexes of modified DIOPs bearing electron-donating groups showed higher catalytic activities than that of original DIOP, and the cationic complexes showed better enantioselectivities than the corresponding neutral ones. The cationic rhodium(I) complex of p-methoxy-substituted DIOP was found to be the most efficient catalyst.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::149785ebe6d7476f3bb48b0f9221f8c5 https://doi.org/10.1248/cpb.40.2894 Zobrazit plný text záznamu