Enhanced Parotid Kallikrein Secretion in Essential, Adrenal Hypertension and in Advanced Renal Failure — Inverse Relationship to Sodium Excretion
| Autor: | G. Stürmer, G. J. Schmid, A. Heidland, A. Röckel |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
medicine.medical_specialty
business.industry Sodium chemistry.chemical_element Kallikrein urologic and male genital diseases medicine.disease Pathogenesis Excretion Primary aldosteronism Blood pressure Endocrinology chemistry Internal medicine Extracellular fluid Medicine business Adrenal hypertension circulatory and respiratory physiology |
| Zdroj: | Hypertension: Mechanisms and Management ISBN: 9783540101710 |
| DOI: | 10.1007/978-3-642-67712-0_17 |
| Popis: | There are several lines of evidence that the renal kallikrein-kinin system (KKS) is altered in various forms of hypertension, probably indicating a defective vasodepressor system as a pathogenetic factor in blood pressure regulation. Urinary kallikrein excretion was found to be decreased in patients with essential [9, 15, 18, 19, 35], renovascular [13] and renoparenchymal hypertension [25, 27] and elevated in primary aldosteronism [18, 27]. Furthermore, a dependence of the activity of the renal KKS on factors involved in the pathogenesis of hypertension (extracellular volume [21], sodium- and potassium balance [1, 10, 19, 22, 26, 36], and mineralocorticoids [19]), was established. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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