Dissociation equilibrium between uncharged and charged local anesthetic lidocaine in a surface-adsorbed film
Autor: | Ikuo Ueda, Shoji Kaneshina, Hiroshi Kamaya, Michio Yamanaka, Hitoshi Matsuki |
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Rok vydání: | 2004 |
Předmět: | |
Zdroj: | Colloid and Polymer Science. 283:512-520 |
ISSN: | 1435-1536 0303-402X |
DOI: | 10.1007/s00396-004-1177-1 |
Popis: | The dissociation equilibrium between uncharged local anesthetic lidocaine (LC) and charged local anesthetic LC (LC•H+) in a surface-adsorbed film was investigated by measuring the surface tension and pH of aqueous solutions of a mixture of hydrochloric acid and LC. The surface tension values decreased slightly with increasing total molality mt at 0≤X2≤0.5, where X2 is the mole fraction of LC in the mixture, while they decreased rapidly with increasing mt at 0.5 |
Databáze: | OpenAIRE |
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