Autor: |
G W Tessmer, Donald J. Graves, T J Carty, J R Skuster, Gerald M. Carlson, R F Parrish |
Rok vydání: |
1975 |
Předmět: |
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Zdroj: |
Journal of Biological Chemistry. 250:2254-2258 |
ISSN: |
0021-9258 |
Popis: |
The interaction between pyridoxal 5'-phosphate and the convertible serine of glycogen phosphorylase has been investigated by using: specific interconverting enzymes, phosphorylase kinase and phosphorylase phosphatase; effectors, glucose and glucose 6-phosphate; and a protein kinase and trypsin. Both phosphorylase kinase and phosphorylase phosphatase utilized the native protein while having little influence on the apoprotein. Removal of a peptide containing the critical serine residue gave phosphorylase b' from which the pyridoxal 5'-phosphate in phosphorylase has an important effect on enzymic interconversion. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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