5-Bromobenzofuran Analog of Chloramphenicol

Autor:	V. V. Badiger, Hanamanthsa S. Bevinakatti
Rok vydání:	1982
Předmět:	McLafferty rearrangement Fragmentation (mass spectrometry) Chemistry Stereochemistry Chloramphenicol Organic Chemistry medicine Electron ionization medicine.drug
Zdroj:	Journal of Heterocyclic Chemistry. 19:69-72
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570190111
Popis:	dl-threo-2-Dichloroacetamido-1-[2-(5-bromobenzofuranyl)] propane-1, 3-diol (7) was synthesised according to Sorm's method. The fragmentation of 2-dichloroacetamido-3-hydroxy-1-[2-(5-bromobenzofuranyl)[-1-propanone (6) under electron impact is reported. The base peak is due to the rupture of the central bond whereas loss of water and McLafferty rearrangement also lead to important fragmentation pathways.
Databáze:	OpenAIRE
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