Tuberculosis – An overview
| Autor: | Nagalambika P, B. Pugazhandhi, S D K Shri Devi, Madurakavi Karthikeyan, Kanthesh M. Basalingappa, Veena Gowda S, Ashok G, Gopenath T S |
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| Rok vydání: | 2021 |
| Předmět: |
Drug
0303 health sciences Tuberculosis biology 030306 microbiology business.industry media_common.quotation_subject General Medicine Drug resistance medicine.disease biology.organism_classification Microbiology Mycobacterium tuberculosis 03 medical and health sciences Chronic infection medicine Efflux Medical science business Bacteria 030304 developmental biology media_common |
| Zdroj: | Indian Journal of Microbiology Research. 8:96-101 |
| ISSN: | 2394-5478 2394-546X |
| DOI: | 10.18231/j.ijmr.2021.019 |
| Popis: | Tuberculosis (TB) is a chronic infection of Mycobacterium tuberculosis. It is spread through the air from person to person and mainly targets the lungs. The tuberculosis epidemic has been complicated by the emergence of drug-resistant TB and HIV-associated TB. In Malaysia, there were an estimated 0.4% of 40,000 TB cases with MDR-TB in 2014. The acquisition of drug resistance in M. tuberculosis is mainly depending on the efflux mechanisms which allow the bacteria to tolerate higher levels of a drug. The evolutionary pathway of drug resistance is influenced by epistasis and bacterial fitness. There are a few risk factors that responsible for the occurrence of drug-resistant TB. Keywords: Tuberculosis, Drugresistant Tuberculosis, Malaysia. |
| Databáze: | OpenAIRE |
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