Reconstruction of Anorganic Mammalian Bone by Surface-Initiated Polymerization of L-Lactide

Autor:	Mark W. Beatty, Jay D. Steinkruger, Kris Hiebner, Troy Wiegand, Bobby Simetich, Jeremy Karr, Jody Redepenning
Rok vydání:	2008
Předmět:	Solvent Chemical kinetics Compressive strength Materials science Polymerization General Chemical Engineering Materials Chemistry L lactide General Chemistry Composite material Mole fraction Elastic modulus Catalysis
Zdroj:	Chemistry of Materials. 20:5016-5022
ISSN:	1520-5002 0897-4756
DOI:	10.1021/cm800895r
Popis:	Polymerization of L-lactide within the pores of anorganic mammalian bone is described. No additional solvent or catalyst is used. The resulting composites exhibit macroscopic morphologies and mechanical properties similar to that of the original bone. We observe an average compressive strength of 194 MPa and an elastic modulus of 8.8 GPa for composites comprised of poly-L-lactide and anorganic bone derived from bovine femurs. Modeling of the reaction kinetics with synthetic sources of crystalline hydroxyapatite powder suggests that polymerization proceeds via a surface-initiated mechanism that is first order in surface area of hydroxyapatite and first order in mole fraction of L-lactide.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::143ba0ba6f5811ae0eb86a6f2bc9db68 https://doi.org/10.1021/cm800895r Zobrazit plný text záznamu