Regular production and supply of ready-to-use gallium-68 radiopharmaceuticals: centralized radiopharmacy concept with supply experience of 300 doses

Autor: V. V. Murhekar, Shubhangi Mirapurkar, Anupam Mathur, Dheeraj Kumar, Sanjeev Kumar, Vrinda Prashant, Soumen Das
Rok vydání: 2021
Předmět:
Zdroj: Journal of Radioanalytical and Nuclear Chemistry. 330:83-90
ISSN: 1588-2780
0236-5731
DOI: 10.1007/s10967-021-07921-7
Popis: The present work illustrates the feasibility of production and supply of ready-to-use gallium-68 (68Ga) radiopharmaceuticals, similar to [18F]FDG, through a centralized production facility. The supply logistic from centralized facility to various imaging centers situated within the radius of 50 km was investigated using germanium-68/gallium-68 generator system of fixed (1.85 GBq) capacity. However, the logistics discussed and conclusion drawn can be definitely extrapolated to many other 68Ga radiopharmaceuticals, where the 68Ga radioisotope used is produced via direct cyclotron route.
Databáze: OpenAIRE