Changes in enzyme activity of leukocytes during amyloid formation experimentally and in patients with amyloidosis

Autor:	T. S. Korneeva, Sura Vv, V. B. Artem'eva, O. P. Kuznetsova, I. A. Komissarova
Rok vydání:	1976
Předmět:	chemistry.chemical_classification Pathology medicine.medical_specialty biology Amyloid Amyloidosis General Medicine medicine.disease General Biochemistry Genetics and Molecular Biology Enzyme assay Resorption Enzyme chemistry Myeloperoxidase Casein Hydrolase biology.protein medicine
Zdroj:	Bulletin of Experimental Biology and Medicine. 82:988-990
ISSN:	1573-8221 0007-4888
Popis:	In patients with secondary amyloidosis and in animals with experimental amyloidogenesis and amyloidosis (casein model) the activity of hydrolases, oxidoreductases, and myeloperoxidase was determined in neutrophils and lymphocytes of the peripheral blood. During the period of amyloid formation, hydrolase and myeloperoxidase activity in the neutrophis was reduced, especially in the stage of initial amyloid deposition. Changes in the activity of these enzymes in animals with developed amyloidosis coincided with those in the blood cells of patients with secondary amyloidosis. The results are discussed from the standpoint of the resorption theory.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::14335f9ff6b64b9cb9ef5cf341738504 https://doi.org/10.1007/bf00789848 Zobrazit plný text záznamu Full text from SpringerLink