Insuficiencia respiratoria grave asociada a infección por metapneumovirus en lactantes
| Autor: | Isabel González L, Ricardo Ronco M, Rafael Torres N, Cesar Cubas R, Gabriel Muñoz R, Astrid Valenzuela S, Jorge Roque E |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Pediatric intensive care unit
Bordetella pertussis Microbiological culture biology Paramyxoviridae business.industry viruses virus diseases Respiratory infection biology.organism_classification Virology respiratory tract diseases Human metapneumovirus Respiratory failure Pediatrics Perinatology and Child Health Respiratory virus Medicine business |
| Zdroj: | Revista chilena de pediatría. 78 |
| ISSN: | 0370-4106 |
| Popis: | Background: In 2001, dutch researchers reported a new virus able to cause high and low acute respiratory infection (ARI) in children. It belongs to the Paramyxoviridae family and constitutes the first human pathogen in the genus Metapneumovirus: human Metapneumovirus (hMPV). Objective: Report a retrospective review of 4 infants with hMPV low ARI with severe respiratory failure, admitted in Pediatric Intensive Care Unit between November 2005 and September 2006 and review the literature. Patients and Methods: Common respiratory virus and Bordetella pertussis were ruled out. Polymerase chain reaction was performed to detect the fusion protein(f)of hMPV and Adenovirus cellular culture. Results: All 4 cases had obstructive bronchial syndrome (OBS), 3 required invasive mechanical ventilation and 2 cases presented spontaneous pneumotorax. Co-infection with Adenovirus was detected in 2 cases. Bacterial cultures were negative. No patients died. Conclusion: hMPV must be suspected in infants with severe acute respiratory failure. The co-infection with Adenovirus must be ruled out. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|