Cytotoxic Inducers in Crohn’s Disease and Ulcerative Colitis

Autor: G. L. Gitnick
Rok vydání: 1982
Předmět:
Zdroj: Inflammatory Bowel Diseases ISBN: 9789400975163
DOI: 10.1007/978-94-009-7514-9_9
Popis: The concept that infectious agents might be causative factors for Crohn’s disease (CD) was first proposed by Crohn et al (1) and for ulcerative colitis (UC) by Bargen (2). Further impetus to research in this area was provided by the reports of Mitchell and Rees (3) and Cave et al (4) that small (less than 220nm) transmissible agents from human tissues induced changes similar to IBD in mice and rabbits.
Databáze: OpenAIRE