Long-term follow-up of childhood Henoch-Sch�nlein nephritis
| Autor: | Cyril Chantler, Rosamund Akuse, Richard H. R. White, Amanda R. Goldstein |
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| Rok vydání: | 1992 |
| Předmět: |
Nephrology
medicine.medical_specialty Pregnancy Proteinuria medicine.diagnostic_test Long term follow up business.industry Disease urologic and male genital diseases medicine.disease Gastroenterology Internal medicine Pediatrics Perinatology and Child Health medicine Renal biopsy medicine.symptom business Henoch-Schonlein nephritis Nephritis |
| Zdroj: | Pediatric Nephrology. 6:398-398 |
| ISSN: | 1432-198X 0931-041X |
| DOI: | 10.1007/bf00869746 |
| Popis: | A study of long-term outcome of 78 subjects who had had Henoch-Schonlein nephritis during childhood (at a mean of 23.4 years after onset) shows that severity of clinical presentation and initial findings on renal biopsy correlate well with outcome but have poor predictive value in individuals. 44% of patients who had nephritic, nephrotic, or nephritic/nephrotic syndromes at onset have hypertension or impaired renal function, whereas 82% of those who presented with haematuria (with or without proteinuria) are normal. 17 patients deteriorated clinically from an initial assessment in 1971; 7 of these had apparently completely recovered in 1976. 16 of 44 full-term pregnancies were complicated by proteinuria and/or hypertension, even in the absence of active renal disease. These findings indicate that childhood Henoch-Schonlein nephritis requires long-term follow-up, especially during pregnancy. |
| Databáze: | OpenAIRE |
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