Biosynthesis of the clerodane furano-diterpene lactone skeleton in Tinospora cordifolia
| Autor: | Kumkum Rani, Anand Akhila, Raghunath S. Thakur |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
chemistry.chemical_classification
biology Geranylgeranyl pyrophosphate Chemistry Stereochemistry Plant Science General Medicine Horticulture Tinospora cordifolia biology.organism_classification Ring (chemistry) Biochemistry chemistry.chemical_compound Biosynthesis Diterpene Menispermaceae Molecular Biology Lactone |
| Zdroj: | Phytochemistry. 30:2573-2576 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/0031-9422(91)85103-7 |
| Popis: | The isotope ratios in cis -clerodane furanoditerpene lactones labelled from [4 R - 3 H 1 , 2- 14 C]MVA suggested two 1,2-hydrogen shifts and two 1,2-methyl shifts during the formation ofthe ring system of these diterpenes. Chemical degradation of clerodane diterpenoids radiolabelled from [2- 14 C]MVA revealed that the gem -methyls of geranylgeranyl pyrophosphate (GGPP) retained their identity during the cyclization. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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