Popis: |
Lung infiltrates in immunocompromised patients have a broad differential diagnosis. Assessment should include considering host risk factors, the clinical presentation, and imaging. Cross-sectional imaging is very helpful and lower respiratory tract samples should be obtained where possible. Laboratory diagnostic tests should be performed but most have low sensitivity and specificity. The differential diagnosis includes non-infective and infective cause. Effective patient management requires good supportive therapy if in respiratory failure, prompt diagnostics, early empiric antimicrobial treatment, and management of the underlying immunosuppression. |