Soluble forms of PD-1/PD-L immune checkpoint receptor and ligand in blood serum of breast cancer patients: association with clinical pathologic factors and molecular type of the tumor

Autor: Elena Sergeyevna Gershtein, E. A. Korotkova, I. K. Vorotnikov, N. Yu. Sokolov, V. D. Ermilova, A. S. Mochalova, N. E. Kushlinskii
Rok vydání: 2022
Předmět:
Zdroj: Russian Clinical Laboratory Diagnostics. 67:76-80
ISSN: 2412-1320
0869-2084
DOI: 10.51620/0869-2084-2022-67-2-76-80
Popis: Results of enzyme-linked immunosorbent assay of the soluble forms of PD-1/PD-L immune checkpoint receptor and ligand (sPD-1 and sPD-L1) in pretreatment blood serum of 88 breast cancer patients at various disease stages aged 30-83 years are presented. The control group included 55 practically healthy women aged 19-82 years. Serum sPD-1 and sPD-L1 levels in breast cancer patients highly significantly (p
Databáze: OpenAIRE