SODIUM DIETHYLDITHIOCARBAMATE AS A SPECTROPHOTOMETRIC REAGENT FOR THE DETERMINATION OF CHLORAL HYDRATE

Autor: Asrar A. Kazi, M. Akhtar Javed, Afifa Mobashar, Islam Ullah Khan, Tehseen Aman, M. A. Kashmiri
Rok vydání: 2001
Předmět:
Zdroj: Analytical Letters. 34:2671-2684
ISSN: 1532-236X
0003-2719
DOI: 10.1081/al-100108413
Popis: Chloral hydrate reacts with sodium diethyldithiocarbamate to give an orange-red colour after heating at 100°C for 3 min. having maximum absorbance at 450 nm. The reaction is selective for chloral hydrate with 0.01 mg/10 ml as visual limit of quantitation and provides a basis for a new spectrophotometeric determination. The reaction obeys Beer's Law from 0.01 to 3 mg/10 ml of chloral hydrate and the relative standard deviation is 0.68%. The quantitative assessment of tolerable amounts of other drugs like aldomet, benzodiazepines, phenytoin sodium, phenobarbitone and naproxen are also studied.
Databáze: OpenAIRE
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