| Autor: |
J.G. Helton, P. B. Neame, J. Hirsh |
| Rok vydání: |
1979 |
| Předmět: |
|
| Zdroj: |
Thrombosis and Haemostasis. |
| ISSN: |
2567-689X |
| DOI: |
10.1055/s-0039-1684799 |
| Popis: |
Thrombocytopenia often complicates bacterial septicemia in the absence of evidence of DIC. Evidence is provided that thrombocytopenia in these patients is caused by adsorption of IgG to platelets (immune thrombocytopenia) which occurs either as a consequence of bacterial injury or adsorption of immune complexes consisting of bacteria or bacterial products and their specific antibodies. Platelet associated IgG (PAIgG) (assayed by inhibition of lysis) was determined in 44 patients with bacterial septicemia. PAIgG was elevated in 8 of 11 thrombocytopenic patients with gram negative septicemia (mean 47 tg IgG/platelet, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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