Solvent-free C–H alkynylation of azulenes

Autor:	Sławomir Szafert, Bartłomiej Pigulski, Agata Jarszak-Tyl
Rok vydání:	2021
Předmět:	chemistry.chemical_compound Molecular wire Solvent free Alkynylation chemistry Organic Chemistry chemistry.chemical_element Reactivity (chemistry) Azulene Combinatorial chemistry Carbon Catalysis Grinding
Zdroj:	Organic Chemistry Frontiers. 8:5674-5680
ISSN:	2052-4129
DOI:	10.1039/d1qo01091c
Popis:	A solvent-free coupling of azulenes with 1-haloalkynes and 1-halopolyynes has been developed. 1-Haloalkynes were used as substrates and the reaction needs only simple grinding of substrates in a mortar with basic Al2O3 without solvents or precious metal catalysts. The reaction works for longer 1-halopolyynes as well and direct introduction of a linear carbon chain up to (CC)4 is possible giving an easy access to azulene end-capped sp-hybridised carbon molecular wires. Finally, further reactivity of the resulting azulenes was tested and two butadiynyl derivatives were transformed into the corresponding thiophenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::137b4a55fb2d9ba6182d250c6ef47fbe https://doi.org/10.1039/d1qo01091c Zobrazit plný text záznamu