Study of Adenosine Deaminase Levels in Patients of Pulmonary Tuberculosis with and Without Pleural Effusion
| Autor: | K Sonone Kanchan, G Varma Santosh, M Sawale Vishal, Nilaanjana Guha Niyogi, G Abhichandani Leela, Abhijeet Joshi |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Tuberculosis medicine.diagnostic_test biology Pleural effusion business.industry respiratory system medicine.disease Gastroenterology respiratory tract diseases Adenosine deaminase Effusion Pulmonary tuberculosis Internal medicine Biopsy medicine biology.protein In patient Tuberculosis pleural effusion business |
| Zdroj: | IOSR Journal of Dental and Medical Sciences. 13:30-37 |
| ISSN: | 2279-0853 2279-0861 |
| DOI: | 10.9790/0853-13193037 |
| Popis: | Tuberculosis (TB) is one of the oldest and commonest infectious diseases also known as "master of death" or "Captain of death". Pulmonary TB(PTB) and TB with pleural effusion remains a diagnostic challenge. Adenosine deaminase(ADA) is an enzyme of purine catabolism which is an inexpensive and easy test in early routine evaluation of patients with pleural effusion and helps to avoid invasive test like biopsy. Therefore, this study was aimed to determine the exact role of ADA in TB patients with and without pleural effusion and in non-tuberculosis pleural effusion and to provide a clear picture of ADA for early diagnosis & management of TB. Materials and method: Study comprised of 132 subjects of which 33 are healthy controls and 33 are confirmed cases of pulmonary TB without effusion, 33 are PTB with effusion and 33 are non-TB effusion patients. Age group range was from 20- 70 years. Estimation of serum and pleural fluid Adenosine deaminase by Guisti and Galanti method of enzymatic analysis. Results: Serum ADA levels in pulmonary tuberculosis (55.09 + 11.02) patients and pulmonary tuberculosis with pleural effusion (44.01 + 7.82) were significantly higher (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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