The role of plant processing for the cancer preventive potential of Ethiopian kale (Brassica carinata)
| Autor: | Grace A. Odongo, Corinna Herz, Monika Schreiner, Nina Schlotz, Susanne Neugart, Franziska S. Hanschen, Sascha Rohn, Evelyn Lamy, Bernhard Trierweiler, Benard Ngwene, Abraham Wahid Luvonga, Susanne Baldermann, Lara Frommherz, Charles M. A. P. Franz |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
chemistry.chemical_classification Aflatoxin 030109 nutrition & dietetics Nutrition and Dietetics biology Brassica carinata Public Health Environmental and Occupational Health food and beverages Brassicaceae biology.organism_classification Crop 03 medical and health sciences chemistry.chemical_compound chemistry Polyphenol Chlorophyll Botany Food science Mycotoxin Carotenoid Food Science |
| Zdroj: | Food & Nutrition Research. 61:1271527 |
| ISSN: | 1654-661X 1654-6628 |
| Popis: | Background: Ethiopian kale (Brassica carinata) is a horticulturally important crop used as leafy vegetable in large parts of East and Southern Africa. The leaves are reported to contain high concentrations of health-promoting secondary plant metabolites. However, scientific knowledge on their health benefits is scarce.Objective: This study aimed to determine the cancer preventive potential of B. carinata using a human liver in vitro model focusing on processing effects on the pattern of secondary plant metabolites and bioactivity.Design: B. carinata was cultivated under controlled conditions and differentially processed (raw, fermented, or cooked) after harvesting. Human liver cancer cells (HepG2) were treated with ethanolic extracts of raw or processed B. carinata leaves and analyzed for their anti-genotoxic, anti-oxidant, and cytostatic potential. Chemical analyses were carried out on glucosinolates including breakdown products, phenolic compounds, carotenoids, and chlorophyll content.Results: P... |
| Databáze: | OpenAIRE |
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