ChemInform Abstract: Synthesis and Relative Binding Affinity to Steroid Receptors and Antiproliferative Activity on MCF-7 Cells of 2,3-Disubstituted Indenes

Autor:	Francoise Bouchoux, Serge Kirkiacharian, Daniel Philibert, Pantelis G. Koutsourakis, Patrick Van De Velde
Rok vydání:	2010
Předmět:	Androgen receptor Biochemistry MCF-7 Estrogen medicine.drug_class Chemistry medicine.medical_treatment medicine General Medicine Antiproliferative effect Receptor Hormone Steroid
Zdroj:	ChemInform. 31
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200006094
Popis:	The study of the relative binding affinity of a set of 2,3-disubstituted indenes to the receptors of steroid hormones indicates a weak effect of some derivatives on estrogen, progesterone and androgen receptors. The antiproliferative effect on human MCF-7 cells also shows a weak activity for three derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1365fe87d6ce4bb02178259443de41ab https://doi.org/10.1002/chin.200006094 Zobrazit plný text záznamu Plný text