Long-term Management of Patients with Bleeding Ulcers: Rationale, Results, and Economic Impact

Autor: Dennis M. Jensen, James V. Egan
Rok vydání: 1991
Předmět:
Zdroj: Gastrointestinal Endoscopy Clinics of North America. 1:367-385
ISSN: 1052-5157
DOI: 10.1016/s1052-5157(18)30676-7
Popis: The only documented cure for bleeding peptic ulcers is surgery. Emergency endoscopic hemostasis is often successful for control of active bleeding and control of rebleeding. Ulcers heal in most patients with medical treatment. The risk of re-ulcerations and rebleeding is high, however, unless patients stay on continuous maintenance H2 receptor antagonists and off nonsteroidal antiinflammatory drugs (NSAIDs) or aspirin. This has been cost effective in some studies for 8 to 20 years compared to surgery. The role of ulcer surgery, NSAIDs, and Heliobacter pylori in recurrent ulceration and rebleeding are discussed, although detailed studies on the subgroup of ulcer bleeders are few.
Databáze: OpenAIRE