Update on the Management of Pancreatic Cancer: Determinants for Surgery and Widening the Therapeutic Window of Surgical Resection
| Autor: | Amer H. Zureikat, Herbert J. Zeh, Melissa E. Hogg, Jason C. Maggi |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Multimodality Therapy Disease 030230 surgery medicine.disease Systemic therapy Surgery 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Pancreatic cancer Medicine Biomarker (medicine) Robotic surgery business Radiation treatment planning Neoadjuvant therapy |
| Zdroj: | Current Surgery Reports. 4 |
| ISSN: | 2167-4817 |
| Popis: | Pancreatic cancer continues to be a disease associated with poor long-term survival. Surgical resection is associated with high morbidity and delays in systemic therapy. Recognition of pancreatic cancer as a systemic disease has led to the increased utilization of multimodality therapy and shifting paradigms in the sequence of care. Identification of biomarkers and improved understanding of tumor biology have allowed for improved patient stratification and an individualized approach to treatment planning. Additionally, introduction of minimally invasive approaches to pancreatic resection have improved rates of significant post-operative morbidity. Cumulatively, these new developments have altered the approach to surgical resection and aid in improving patient survival. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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