The convenient synthesis and reaction of 2-(arylthio)phenols under ligand-free conditions: arylthioquinone preparation through cascade C–H functionalization and oxidation from arylthiols and aryl iodides

Autor:	Zhaojun Xu, Huida Wan, Wei Yao, Dawei Wang, Xiaoli Yu, Likui Wang
Rok vydání:	2016
Předmět:	010405 organic chemistry Ligand Aryl Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Nitrogen 0104 chemical sciences Quinone chemistry.chemical_compound chemistry Drug Discovery Organic chemistry Surface modification Phenols
Zdroj:	Tetrahedron Letters. 57:5211-5214
ISSN:	0040-4039
Popis:	A convenient and simple method for copper-catalyzed synthesis of 2-(arylthio)phenols through C–H functionalization of arylthiols and aryl iodides was developed under ligand-free conditions without nitrogen protection. In addition, arylthioquinone derivatives were very easily prepared for one more step of oxidation with moderate to good yields. This provide an alternative and efficient way to 2-(arylthio)phenols and arylthioquinone derivatives smoothly without using ligands and nitrogen protection or expensive arylboronic acids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::13532febe33656f8c95df2987ea3c3b9 https://doi.org/10.1016/j.tetlet.2016.10.028 Zobrazit plný text záznamu Full Text from ScienceDirect