Serum leptin and insulin concentrations in prepubertal lean, obese and insulin-dependent diabetes mellitus children
| Autor: | Akira Matsui, Tomohiro Kamoda, Hisako Saitoh, Takeki Hirano, Ishou Izumi, Satoko Nakahara |
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| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
business.industry Endocrinology Diabetes and Metabolism Insulin medicine.medical_treatment Leptin nutritional and metabolic diseases Radioimmunoassay medicine.disease Obesity Endocrinology Internal medicine Diabetes mellitus Blood plasma medicine business Body mass index Pancreatic hormone |
| Zdroj: | Clinical Endocrinology. 49:385-389 |
| ISSN: | 0300-0664 |
| DOI: | 10.1046/j.1365-2265.1998.00538.x |
| Popis: | OBJECTIVE To evaluate the relationship between serum levels of leptin and insulin in prepubertal lean, obese and insulin-dependent diabetes mellitus (IDDM) children. SUBJECTS AND MEASUREMENTS Prepubertal children, 16 lean, 17 obese and 16 IDDM were included in the study. Fastang serum leptin and insulin concentrations were measured by radioimmunoassays. RESULTS The serum level of leptin was significantly higher in obese children than in lean and IDDM children (P |
| Databáze: | OpenAIRE |
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