Validity of the DESPAR questionnaire as a new screening tool for depression in Parkinson’s disease
| Autor: | Michael Bauer, G Reifschneider, Christine Schneider, Per Odin, Bernd Leplow, Heinz Reichmann, Georg Ebersbach, Wolfgang H. Jost, Alexander Storch, Yvonne Paelecke-Habermann, G. Fuchs |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Parkinson's disease Receiver operating characteristic Gold standard Beck Depression Inventory medicine.disease External validity Neurology Cronbach's alpha medicine Physical therapy Neurology (clinical) Psychology Depression (differential diagnoses) Clinical psychology Mini-international neuropsychiatric interview |
| Zdroj: | Basal Ganglia. 1:97-103 |
| ISSN: | 2210-5336 |
| DOI: | 10.1016/j.baga.2011.04.003 |
| Popis: | Objective To validate the DEpression Screening in PARkinson’s disease (DESPAR) self-administered questionnaire, a subscale of a recently developed new screening tool for secondary depression. Background Although depression has a high prevalence in PD, it often remains undetected. Currently, the Beck Depression Inventory (BDI-1A) is the gold standard screening tool for PD depression, but as a result of its length and complexity it is of limited suitability as a quick and easy screening device. The DESPAR is a short 15-item self-administered questionnaire especially designed for the screening of depression in PD. Methods We assessed 215 Patients with PD (mean [SD] age: 68 ± 9 years) at Hoehn and Yahr stages I–V (median: II.0) in a multicenter study using the DESPAR and the BDI-1A. Psychiatric diagnoses were made using the structured Mini International Neuropsychiatric Interview (M.I.N.I). External validity for detection of depression and combined depression/dysthymia was evaluated by receiver operating curve (ROC) analysis. Results Two hundred and eleven patients (98.1%) completed the DESPAR. Internal consistency of the DESPAR was good (Cronbach’s α = 0.91). ROC analysis showed that both questionnaires adequately detected depression without differences in the validity indices (0.897 [95%CI: 0.838–0.956] for DESPAR; AUC 0.924 [95%CI: 0.887–0.960] for BDI-1A; P = 0.463). The optimal cut-off value for detection of depression and combined depression/dysthymia with equal sensitivity and specificity was 29/30 points. Conclusion The DESPAR showed good internal reliability and external validity for screening for depression and dysthymia in PD. It is thus a useful, brief and easy instrument for identifying PD subjects with depression/dysthymia in daily practice. |
| Databáze: | OpenAIRE |
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