Solid state reactions of nitrogenous heterocyclic compounds (II)

Autor:	Yongmei Wang, Da-Ming Du, Zhong Wen, Guo-Xiang Xiong, Jiben Meng, Xiaoliu Li
Rok vydání:	1997
Předmět:	Indole test Crystal Chemistry Yield (chemistry) Proton NMR Michael reaction General Chemistry Lewis acids and bases Condensation reaction Selectivity Medicinal chemistry
Zdroj:	Science in China Series B: Chemistry. 40:270-277
ISSN:	1862-2771 1006-9291
DOI:	10.1007/bf02877728
Popis:	Solid state Michael addition reaction of indole with α, β-unsaturated carbonyl compounds was carried out, by which a series of compounds containing three different heterocyclic groups binding to one carbon atom were ob-tained. In the presence of Lewis acid, indole could undergo the solid state condensation reaction with aromatic ketones and aldehydes or quinones. The solid state reaction showed higher selectivity and yield than solution reaction. The structures of products were identified by IR,1H NMR, MS. elemental analysis and X-ray crystal analysis. The reac-tion mechanism was also proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1323c5701c82072090289b83716ac05f https://doi.org/10.1007/bf02877728 Zobrazit plný text záznamu Full text from SpringerLink