Giant cell granulamatous hypophysitis with remarkable uptake on Gallium-67 scintigraphy
| Autor: | Akihiro Ishizu, Takao Koike, Tsutomu Katoh, Mitsumasa Kubo, Chikara Shimizu, Hiromichi Kijima |
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| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Pathology Pituitary gland medicine.diagnostic_test business.industry Hypophysitis Endocrinology Diabetes and Metabolism Langhans giant cell Magnetic resonance imaging medicine.disease Scintigraphy Endocrinology medicine.anatomical_structure Giant cell Internal medicine Diabetes insipidus Biopsy medicine business |
| Zdroj: | Clinical Endocrinology. 49:131-134 |
| ISSN: | 0300-0664 |
| DOI: | 10.1046/j.1365-2265.1998.00417.x |
| Popis: | We treated a man with giant cell granulomatous hypophysitis with pituitary enlargement, as seen on magnetic resonance imaging. Endocrinological examination revealed panhypopituitarism and diabetes insipidus. Microscopic examination of the specimen obtained by transsphenoidal pituitary biopsy revealed a granulomatous lesion, composed of epitheliod cells, Langhans' multinucleated giant cells, lymphocytes and other chronic inflammatory cells. On whole body gallium-67 scintigraphy, there was extensive uptake in the pituitary gland. Gallium-67 scintigraphy may greatly aid in the diagnosis of granulomatous hypophysitis. |
| Databáze: | OpenAIRE |
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