Origin, evolution, and migration of drug resistance genes

Autor:	Zh. M. Gorlenko, I. A. Bass, Mayya Petrova, Sofia Mindlin
Rok vydání:	2006
Předmět:	Multiple drug resistance Genetics Plasmid Horizontal gene transfer Microbial genetics Drug resistance Mobile genetic elements Biology biology.organism_classification Gene Bacteria Microbiology
Zdroj:	Russian Journal of Genetics. 42:1257-1271
ISSN:	1608-3369 1022-7954
Popis:	Current views on the mechanisms responsible for the emergence of multiple drug resistance in clinical bacterial isolates are considered. Hypotheses on the origin of resistance genes derived from determinants of actinomycetes, antibiotic producers, and chromosomal genes of bacteria involved in cellular metabolism are reviewed. The mechanisms underlying the diffusion of resistance determinants by means of bacterial mobile elements (plasmids, transposons, and integrons) are discussed. Examples of the horizontal transfer of resistance determinants between Gram-positive and Gram-negative bacteria are presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::13051b52feb75590ba0c9339d98c7b46 https://doi.org/10.1134/s1022795406110081 Zobrazit plný text záznamu Full text from SpringerLink