MeOPEG-bounded azide cycloadditions to alkynyl dipolarophiles
Autor: | Giorgio Molteni, Luisa Garanti |
---|---|
Rok vydání: | 2003 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 44:1133-1135 |
ISSN: | 0040-4039 |
DOI: | 10.1016/s0040-4039(02)02844-7 |
Popis: | The MeOPEG-supported azide 2 was reacted in the presence of a number of alkynyl dipolarophiles. The corresponding 1-MeOPEG-supported-1,2,3-triazoles were obtained in nearly quantitative yields. Acidic hydrolysis of the cycloadducts 5b and 6b caused the removal of the MeOPEG pendant giving 4-methoxycarbonyl-1,2,3-triazole 9 and 5-methoxycarbonyl-1,2,3-triazole 10 , respectively. |
Databáze: | OpenAIRE |
Externí odkaz: |