MeOPEG-bounded azide cycloadditions to alkynyl dipolarophiles

Autor: Giorgio Molteni, Luisa Garanti
Rok vydání: 2003
Předmět:
Zdroj: Tetrahedron Letters. 44:1133-1135
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02844-7
Popis: The MeOPEG-supported azide 2 was reacted in the presence of a number of alkynyl dipolarophiles. The corresponding 1-MeOPEG-supported-1,2,3-triazoles were obtained in nearly quantitative yields. Acidic hydrolysis of the cycloadducts 5b and 6b caused the removal of the MeOPEG pendant giving 4-methoxycarbonyl-1,2,3-triazole 9 and 5-methoxycarbonyl-1,2,3-triazole 10 , respectively.
Databáze: OpenAIRE