Entérocolite ulcéronécrosante chez un nouveau-né à terme. Rôle de l'acyclovir?
| Autor: | P. Olivier, C. Damase-Michel, N. Montjaux-Régis, A. Chanot, C. Casper, C. Mengelle, I. Glorieux |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Pediatrics Pregnancy Nucleoside analogue Vaginal delivery business.industry viruses virus diseases Gestational age biochemical phenomena metabolism and nutrition medicine.disease Surgery In utero Pediatrics Perinatology and Child Health Necrotizing enterocolitis medicine heterocyclic compounds Aciclovir business Herpes Genitalis medicine.drug |
| Zdroj: | Archives de Pédiatrie. 14:1420-1423 |
| ISSN: | 0929-693X |
| Popis: | Acyclovir is a synthetic nucleoside analogue active against herpes viruses. Exposure during human pregnancy and during the neonatal period seems safe. We report a case of early necrotizing enterocolitis in a full term infant treated with acyclovir as a prophylactic therapy. The mother had herpes genitalis with preterm, premature ruture of membranes at 32 weeks of gestational age and was treated with acyclovir until vaginal delivery. Acyclovir treatment in utero and after birth is discussed as a possible cause of necrotizing enterocolitis in the infant. Acyclovir should be used only if its benefit outweighs the potential risk to the baby. |
| Databáze: | OpenAIRE |
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