Specifics of anaphase chromatid segregation in Drosophila melanogaster mitotic mutants

Autor:	L. I. Lebedeva, Leonid V. Omelyanchuk, S. A. Fedorova
Rok vydání:	2008
Předmět:	Genetics biology Mutant Wild type Chromatid Context (language use) Drosophila melanogaster biology.organism_classification Mitosis Cell Cycle Gene Anaphase
Zdroj:	Russian Journal of Genetics. 44:919-927
ISSN:	1608-3369 1022-7954
DOI:	10.1134/s102279540808005x
Popis:	Anaphase chromatid segregation defects (CSDs) were quantitatively and qualitatively studied in neural ganglion cells of third-instar larvae of several control wild type Drosophila melanogaster strains and four strains with mutations of the aar v158 , ff3, mast v40 , and CycB 2g cell cycle genes. A linear specificity was observed for the CSD frequency, type, determination, and correction probability. The probability of anaphase CSD correction was close to unity in the control strains and lower in the mutant strains. The lower correction probability in the mutant strains was explained in the context of two findings, that the mutations induced the CSDs that were atypical of the wild type strains and were potentially uncorrectable in anaphase and that the mutations negatively affected the relative anaphase time in mitosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::12e2e13b1266b50557ed4b40a8578fc5 https://doi.org/10.1134/s102279540808005x Zobrazit plný text záznamu Full text from SpringerLink