High prevalence of diffuse large B-cell lymphoma in occult hepatitis B virus-infected patients in the Tohoku district in Eastern Japan
| Autor: | Yuichi Kato, Jugoh Itoh, Masaharu Wano, Naoto Takahashi, Kazunori Murai, Kenichi Ishizawa, Yoji Ishida, Tomoaki Akagi, Hideyoshi Noji, Katsushi Tajima, Hideo Harigae, Osamu Sasaki, Tsutomu Scichishima, Kenichi Sawada |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Hepatitis Hepatitis B virus business.industry Incidence (epidemiology) virus diseases Spleen Hepatitis B medicine.disease medicine.disease_cause Occult Virology digestive system diseases Lymphoma 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Infectious Diseases medicine.anatomical_structure 030220 oncology & carcinogenesis medicine business Diffuse large B-cell lymphoma |
| Zdroj: | Journal of Medical Virology. 88:2206-2210 |
| ISSN: | 0146-6615 |
| DOI: | 10.1002/jmv.24584 |
| Popis: | Occult hepatitis B virus (HBV) infection is a clinical challenge, but its relationship to clinicopathologic features and the risk of progression to malignant lymphoma (ML) are poorly defined. We estimated the prevalence of HBV infection of 1,358 patients with newly diagnosed ML. HBV infection was more prevalent in ML than in control patients. The occult HBV infection group had a higher median onset age, no liver or spleen involvement, and higher prevalence of diffuse large B-cell lymphoma than the other groups, indicating that occult HBV infection is a distinct clinicopathologic entity. J. Med. Virol. 88:2206-2210, 2016. © 2016 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text