SpO2/FIO2 on Presentation as a Predictor for Early Hemodynamic Deterioration in Intermediate Risk Acute Pulmonary Embolism
| Autor: | Mehrdad Ghahramani, Ryan Rogers, Lisa Domaradzki, Andry Van de Louw, Ryan Wilson, Mohammed Ruzieh |
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| Rok vydání: | 2019 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Univariate analysis education.field_of_study business.industry Population Hemodynamics General Medicine Hypoxia (medical) Critical Care and Intensive Care Medicine medicine.disease Pulmonary embolism medicine.anatomical_structure Ventricle Interquartile range Internal medicine medicine Cardiology Decompensation medicine.symptom business education |
| Zdroj: | Respiratory Care. 64:1279-1285 |
| ISSN: | 1943-3654 0020-1324 |
| DOI: | 10.4187/respcare.06797 |
| Popis: | BACKGROUND: Patients with intermediate-risk acute pulmonary embolism are at risk of hemodynamic deterioration, and identification of risk factors for decompensation could guide the administration of thrombolytics. We aimed to assess whether SpO2/FIO2 on presentation is associated with early hemodynamic deterioration in this population. METHODS: A retrospective chart review of subjects admitted between 2006 and 2018 with intermediate-risk pulmonary embolism (hemodynamically stable with right ventricle to left ventricle ratio > 0.9 or tricuspid annular plane systolic excursion RESULTS: A total of 178 subjects were included. Early hemodynamic deterioration occurred in 13% of the subjects and was associated with a median (interquartile range) lower SpO2/FIO2 on presentation in univariate analysis (243 [123–275] versus 438 [335–457], P CONCLUSIONS: In intermediate-risk pulmonary embolism, SpO2/FIO2 on presentation can help predict the risk of early hemodynamic deterioration. |
| Databáze: | OpenAIRE |
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