Vindesine in refractory multiple myeloma
| Autor: | Albert E. G. Kr. von dem Borne, Ed Monasch, Hans van der Lelie, Hans G. Pegels |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Melphalan
Oncology Cancer Research medicine.medical_specialty Chemotherapy Vincristine Cyclophosphamide business.industry Myeloma protein medicine.medical_treatment Pharmacology medicine.disease Prednisone hemic and lymphatic diseases Internal medicine Medicine Vindesine business Multiple myeloma medicine.drug |
| Zdroj: | Cancer. 57:226-229 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19860115)57:2<226::aid-cncr2820570207>3.0.co;2-i |
| Popis: | In 12 of 18 patients with multiple myeloma refractory to treatment with the combination of vincristine, melphalan, cyclophosphamide, and prednisone, favorable results were obtained by replacing vincristine in this combination with vindesine. Although only three patients showed marked reductions (greater than 50%) of myeloma protein, this treatment, which was well tolerated, was also clearly beneficial to the other responding patients, thus postponing the need for more toxic treatment programs. |
| Databáze: | OpenAIRE |
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