Reversible Panmyelopathie nach Captopril-Medikation

Autor:	F. Henschke, H.-J. König, H. Iro
Rok vydání:	2008
Předmět:	Drug Creatinine medicine.medical_specialty business.industry media_common.quotation_subject Urology Captopril Histology General Medicine Degeneration (medical) Polycystic kidney chemistry.chemical_compound chemistry Cytology medicine PANMYELOPATHY business medicine.drug media_common
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 111:139-141
ISSN:	1439-4413 0012-0472
Popis:	In a 46-year-old female patient suffering from renal hypertension due to polycystic kidney degeneration with creatinine values between 3 and 5 mg/dl leucopenia developed 3 weeks after beginning antihypertensive therapy with the angiotensin-converting-enzyme inhibitor captopril. On continuation of treatment signs of haemorrhagic diathesis appeared 7 months later. Cytology and histology led to the diagnosis of panmyelopathy which, from the clinical findings and the close patient follow-up, was to be regarded as captopril-induced. Bone-marrow regeneration could be shown 6 months after discontinuing the drug. In renal insufficiency, captopril treatment should be monitored using regular haematological tests and the drug withdrawn when leuco- or thrombocytopenia occurs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::128a02a4427e1341119da44515b62c99 https://doi.org/10.1055/s-2008-1068415 Zobrazit plný text záznamu