Lipase-catalyzed asymmetric hydrolysis and regioselective bromination of 1,4-dihydropyridine. Synthesis of (R)-(=)-nilvadipine
Autor: | Hirosato Ebiike, Kazuo Achiwa |
---|---|
Rok vydání: | 1994 |
Předmět: | |
Zdroj: | Tetrahedron: Asymmetry. 5:1447-1450 |
ISSN: | 0957-4166 |
Popis: | Homochiral ( R )-nilvadipine was synthesized from a prochiral substrate using lipase-catalyzed asymmetric hydrolysis and subsequent regioselective bromination as key steps. |
Databáze: | OpenAIRE |
Externí odkaz: |