Ultrastructural Study of the Macrophage-Cytophilic Antibody-Spermatozoa Complex

Autor:	Clydes Barrera, Alicia B. Mazzolli, O. Vilar
Rok vydání:	1979
Předmět:	Urology Endocrinology Diabetes and Metabolism Phagocytosis Cell Lymphokine Biology Molecular biology In vitro Guinea pig medicine.anatomical_structure Reproductive Medicine Immunology Ultrastructure biology.protein medicine Macrophage Antibody
Zdroj:	International Journal of Andrology. 2:230-240
ISSN:	1365-2605 0105-6263
DOI:	10.1111/j.1365-2605.1979.tb00056.x
Popis:	Normal guinea pig peritoneal cells were firstly incubated in vitro with cytophilic sera obtained from animals with experimental immunologic orchitis and secondly with immobilized spermatozoa from the same cell donor guinea pig. These preparations were studied by transmission and scanning electron microscopy. The results showed that most of peritoneal cells were macrophages which were turned capable to phagocytose normal sperm cells after being incubated with cytophilic serum. This specific phagocytosis seems to be neither complement nor lymphokine dependent. The possible role of cytophilic antibodies in the phagocytic process is discussed.
Databáze:	OpenAIRE
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