Influence of Drugs on Chicken Embryo and on Its Reaction to Sera Containing Forssman Antibodies
| Autor: | Erwin Neter, Ernst Witebsky |
|---|---|
| Rok vydání: | 1935 |
| Předmět: |
Bradycardia
medicine.medical_specialty animal structures biology Digitalis Embryo biology.organism_classification General Biochemistry Genetics and Molecular Biology Atropine chemistry.chemical_compound Endocrinology Epinephrine chemistry Internal medicine embryonic structures Immunology medicine Ergotamine medicine.symptom Acetylcholine Histamine medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 32:725-728 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-32-7835c |
| Popis: | Summary1. In spite of the fact that histamine is able to cause reactions similar to anaphylactic phenomena in other animals, it does not produce in the chicken embryo the vascular phenomenon which follows the addition of Forssman antibody containing serum. 2. Drugs, such as acetylcholine, atropine, epinephrine, ergotamine, likewise fail to produce any reaction similar to the vascular phenomenon. 3. Drugs of the digitalis group induce bradycardia, irregularity and eventually produce cardiac standstill. 4. Chloroform stops the heart beat. With low concentrations of chloroform, a temporary cardiac standstill is produced. 5. Chicken embryos, treated with chloroform in a dosage Which causes a temporary cardiac standstill react as normal embryos to the addition of effective serum, i. e., they show typical vascular phenomenon. 6. The phenomenon cannot be produced in embryos whose heart beat is stopped by exposure to ice box temperature. |
| Databáze: | OpenAIRE |
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