Effects of Cryoprecipitate on the Healing of Chronic Wounds

Autor:	Samuel Cucinell, Thomas K. Hathaway, Sarah S. Steinbaum
Rok vydání:	1994
Předmět:	Chronic wound medicine.medical_specialty integumentary system business.industry Public Health Environmental and Occupational Health Wound surface General Medicine Diabetic ulcers Surgery Basic research Cryoprecipitate Medicine In patient medicine.symptom business Wound healing
Zdroj:	Military Medicine. 159:105-108
ISSN:	1930-613X 0026-4075
DOI:	10.1093/milmed/159.2.105
Popis:	Basic research has promise for clinical wound healing. Purified wound healing growth factors are not available for clinical use, but they are present in plasma and platelets and have been used in patients. Chronic wounds would seem to be good for study since the wound surface is easily measured and the patient is anxious for progress. We have done a double-blinded pilot study using autologous cryoprecipitate on chronic wounds. Three of six patients showed wound healing progress; but only one patient's wounds healed permanently. One patient developed new diabetic ulcers, and one patient failed to keratinize epithelialized skin. Cryoprecipitate may promote wound healing, but further work awaits more purified healing factors. Simple measurement of the surface area of a chronic wound may not be adequate to describe all the processes of healing.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::12416fef160be31a2c614b9bf5925b62 https://doi.org/10.1093/milmed/159.2.105 Zobrazit plný text záznamu