Retinal Artery Contraction After Phenylephrine as a Cardiovascular Risk Biomarker
| Autor: | Alicia López-de-Eguileta, Soraya Fonseca, Andrea Cerveró, Jorge Gaitán, Alfonso Casado |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Contraction (grammar) business.industry Cardiovascular health Retinal Artery 03 medical and health sciences Ophthalmology 0302 clinical medicine medicine.anatomical_structure Coronary risk Internal medicine Healthy control 030221 ophthalmology & optometry Cardiology Medicine sense organs Enhanced depth imaging business Phenylephrine 030217 neurology & neurosurgery medicine.drug Artery |
| Zdroj: | Clinical Ophthalmology. 14:1269-1275 |
| ISSN: | 1177-5483 |
| DOI: | 10.2147/opth.s247680 |
| Popis: | Background and Aim We investigated the in vivo changes of artery diameter (AD) and vein diameter (VD) after topical phenylephrine 2.5% instillation, and its relationship with the Systematic Coronary Risk Evaluation (SCORE). Methods This is a cross-sectional study. Healthy control patients were included. All of the participants underwent enhanced depth imaging by spectral-domain optical coherence tomography before and 30 minutes after phenylephrine instillation, using eye-tracking and follow-up software. Changes in AD and VD were assessed. Results The study included 45 eyes of 45 patients (14 males and 31 females). The mean age was 58.6 ± 15.1 years (26-88 years). Mean SCORE risk estimation value was 2.0 (0-14). No significant correlation was found between pre-phenylephrine AD or VD with age (p=0.237 and p=0.821, respectively), SCORE (p=0.545 and p=0.723, respectively). AD significant thinned after phenylephrine (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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