Imaging of biomolecules with the scanning tunneling microscope: Problems and prospects
| Autor: | W. Siekhaus, D. F. Ogletree, José Antonio Odriozola, T. Wilson, Thomas P. Beebe, Miquel Salmeron |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
chemistry.chemical_classification
Scanning electron microscope Biomolecule Nanotechnology Surfaces and Interfaces Substrate (electronics) Conductivity Condensed Matter Physics Surfaces Coatings and Films law.invention Tunnel effect chemistry law Electron microscope Scanning tunneling microscope Biological imaging |
| Zdroj: | Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films. 8:635-641 |
| ISSN: | 1520-8559 0734-2101 |
| DOI: | 10.1116/1.576361 |
| Popis: | The capabilities of the scanning tunneling microscope as a tool to study the morphology and structure of adsorbed biomolecules are reviewed in view of recent experimental results. Problems such as electrical conductivity of the biomolecules, fixation to the substrate and identification are analyzed in detail. In particular, the role of tip–surface interaction giving rise to repulsive forces is illustrated. It is concluded that fixation rather than conductivity is the major obstacle to the use of the STM for biological imaging. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|