Identification of novel allosteric inhibitors through fragment-based drug discovery and X-ray crystallography

Autor:	O'Brien, P.A. Williams, G. Chessari, M.G. Carr, S. Hiscock, P. Pathuri, Joseph E. Coyle, M. Vinkovic, T. Sambrook, C. Richardson, Anne Cleasby, J.R. Yon, M. Congreve, S. Saalau-Bethell, H. Jhoti, V. Lock, A.J. Woodhead, Christopher William Murray, B. Graham, V Berdini, Sharna J. Rich
Rok vydání:	2015
Předmět:	Inorganic Chemistry Structural Biology Chemistry Stereochemistry Fragment-based lead discovery X-ray crystallography Allosteric regulation General Materials Science Identification (biology) Physical and Theoretical Chemistry Condensed Matter Physics Biochemistry
Zdroj:	Acta Crystallographica Section A Foundations and Advances. 71:s38-s38
ISSN:	2053-2733
DOI:	10.1107/s2053273315099398
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::12042e1cee002767ecb265983acc5045 https://doi.org/10.1107/s2053273315099398 Zobrazit plný text záznamu Plný text